Xu Peng – University of Copenhagen

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Xu Peng

Dr. Xu Peng is a group leader in studying Sulfolobus host-virus interactions, viral genomics and structural proteomics.

Contact information

Department of Biology
University of Copenhagen
Ole Maaløes Vej 5
DK-2200 Copenhagen N
+45 353 22018
peng@bio.ku.dk

Research interests

Virus-host interactions in the model archaeon Sulfolobus; virus life cycle; CRISPR-Cas; biotechnological exploitation of thermophilic archaea and their viruses.

Education

  • 1990 BSc, Biochemistry, Wuhan University, China
  • 1996 MSc, Cell Biology, Paris-Sud University, France
  • 2002 PhD, Biochemistry, Copenhagen University, Denmark

Employment

  • 2002-2006 Assistant Research Professor. Institute of Molecular Biology and Physiology, University of Copenhagen, Denmark
  • 2007-2010 Associate Research Professor. Department of Biology, Biocenter, University of Copenhagen, Denmark
  • From 2010, Associate Professor. Department of Biology, Biocenter, University of Copenhagen, Denmark

Maternity leaves

  • 1997-1998
  • 2002

Grants

  • 2002-2005 Postdoc (STVF) 
  • 2005-2008 Steno (FNU) 
  • 2008-2010 University FRC postdoc
  • 2010 EMBO short term fellowship
  • 2011 – 2015 EU FP7 collaborative project “HotZyme”
  • 2014 – 2016 EU Marie-Curie grant

Teaching experiences

  • Supervision of students:
    • 2005-2008 - 4 bachelor student projects (6 months each)
    • 4 trainee technicians (12 months each)
    • 1 master student project (12 month)
  • Lectures:
    • 2005 – Lab practical course for Biochemistry 3 (10 days)
    • 2005–2007 lectures Biochemistry 2 and Advanced Bacteriology (6 hours)
    • 2008 – eksaminatorier in Biology A2 (18x 2 hours)

International experiences

  • 1994-1996 Master study at Paris-Sud University, France
  • 1996-1997 Research assistant at Institut Curie, Paris, France
  • 2005 Oct. Visiting scientist at St Andrews University, Scotland
  • 2006 Aug.–Sept. Visiting scientist at Pasteur Institute, Paris
  • 2010 July – Nov Visiting scientist at Oxford University, UK

Selected Publications

  • Fei He, Gisle Vestergaard, Wenfang Peng, Qunxin She, Xu Peng; CRISPR-Cas type I-A Cascade complex couples viral infection surveillance to host transcriptional regulation in the dependence of Csa3b. Nucleic Acids Res 2017; 45 (4): 1902-1913. doi: 10.1093/nar/gkw1265
  • Uldahl KB, Wu L, Hall A, Papathanasiou P, Peng X*, Moghimi SM* (2016) Recognition of extremophilic archaeal viruses by eukaryotic cells: a promising nanoplatform from the third domain of life. Scientific Reports, 6: 37966. doi:10.1038/srep37966 (*co-senior author).
  • Martínez-Alvarez L, Bell SD, Peng X. (2016) Multiple consecutive initiation of replication producing novel brush-like intermediates at the termini of linear viral dsDNA genomes with hairpin ends. Nucleic Acids Research. 44: 8799-8809. Doi: 10.1093/nar/gkw636
  • Gudbergsdóttir SR, Menzel P, Krogh A, Young M, Peng X. (2016) Novel viral genomes identified from six metagenomes reveal wide distribution of archaeal viruses and high viral diversity in terrestrial hot springs. Environ. Microbiol. 18: 863-874
  • Guo Y, Kragelund BB, White MF, Peng X (2015) Functional Characterization of a Conserved Archaeal Viral Operon Revealing Single-Stranded DNA Binding, Annealing and Nuclease Activities. J. Mol. Biol. 427(12):2179-91.

Direct to Papers by Dr. Xu Peng to see the full publication list.